Isolation of phenolic compounds from the methanolic extract of Tectona grandis

Phenolic compounds like phenolic acids, flavonoids and tannins are important plant metabolites that are important for many pharmacological activites.we had earlier demonstrated the wound healing activity, analgesic and anti inflammatory of the methanolic extract. The extract was investigated to determine the nature of the phytoconstituents responsible for these activities and this led to the isolation of gallic acid, ellagic acid, rutin and quercitin from the methanolic extract of the leaves of Tectona grandis. Phenolic compounds gallic acid ellagic acid (phenolic acids), rutin and quercitin(flavonoids) were isolated and identified by their melting points, chemical tests, IR, NMR and mass spectra. The isolated compounds were qualified by comparison with the Rf values of that of the standards. Presence of these four phenolic compounds in the methanolic extract of the leaves of Tectona grandis may be an important contributing factor for these activities.